ICPE 2016, Dublin

06 Sep 2016

by Anthony Matthews and Sarah-Jo Sinnot conferencecentre

Members of the EHR group recently travelled to the 32nd International Conference on Pharmacoepidemiology and Therapeutic Risk Management in Dublin. Not only were several members presenting both talks and posters (see table below), the group also held a successful symposium entitled ‘Optimal Use of Data from United Kingdom Electronic Health Records’ during the Saturday afternoon session of the conference.

Thursday academiuc
The conference officially kicked off on Friday 26th August within the futuristic walls of the Dublin conference centre, but Thursday evening saw the academic showcase; a chance for delegates to chat to relevant institutions about their research and courses. The EHR group had a stand predominantly providing information on the short course in Pharmacoepidemiology and Pharmacovigilance (http://goo.gl/bHhvJh). As the drinks began to flow and conversation became more fluent, there was a lot of interest in the course. Hopefully we’ll see some familiar faces at the course next year.

As a sunny Friday morning beckoned the start of the conference, Professor Stephen Evans was the first member of the group to present.  With his engaging arguments and witty stories, he educated delegates on representative sampling in Pharmacoepidemiology and with one mention of “Eton Mess” (ask Stephen, I’m sure he’d be delighted to tell you the joke), the conference was in full swing. The day saw an array of interesting posters, the first set of research presentations, and several committee meetings. Talks ranged from adverse effects of cardiovascular treatment, to data visualisation of health.  By 6.30pm, with full minds and empty stomachs, the group headed into the historic centre of Dublin for a well-earned dinner.


Saturday was a very busy day for our group with more poster and oral presentations. The highpoint of the day however, was the symposium we had organised with our collaborators at CPRD; a government agency responsible for handling de-identified primary care data for resynposiumsearch purposes. The symposium was a 90-minute session detailing some of our work, which falls under an umbrella theme of understanding more clearly the data we use in our research. This work is of huge interest to other researchers and so we had a very big audience in attendance. We presented our work on; defining pregnancies in the dataset; defining cases of cancer; accurately defining kidney outcomes; dealing with problems of under-reporting of ethnicity; using the data to conduct clinical trials with; and combining the data with other similar data sets so that rare diseases can be studied. What was a very busy day finished off with a very busy evening at the Guinness Storehouse for some Guinness (it’s good for you!), food and dancing.

The last day of the conference saw a very early start for some of our group presenting in the morning sessions. After a plenary session which explored how data from many countries can be combined to study drug safety, we had one last lunch, one last run around the posters, one last parallel oral session, and then it was time to say goodbye to ICPE and goodbye to Dublin. Luckily, it won’t be long until we see our international colleagues again; the mid-year meeting of ICPE will be held in London in April 2017. We’re looking forward to it already!

Here are the deatils of the talks and posters all members of our group presented over the weekend.

Name Presentation Title
Caroline Minassian Symposium Identifying Pregnancies in CPRD Primary Care Data
Masao Iwagami Symposium Validity of estimated prevalence of decreased kidney function and renal replacement therapy from primary care electronic health records compared to national survey and registry data in the UK
Sarah-Jo Sinnott Poster The comparative effectiveness of 4th line anti-hypertensive agents in patients with resistant hypertension: a systematic review and meta-analysis
Sarah-Jo Sinnott Poster Estimating the prevalence and incidence of type 2 diabetes mellitus using population level pharmacy claims data
Anthony Matthews Presentation Impact of Statin-Related Media Coverage on the Use of Statins: An Interrupted Time Series Analysis Using UK Primary Care Data
Anthony Matthews Poster Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink
Ian Douglas Presentation The Association Between Lansoprazole and Tuberculosis Disease; a Primary Care Based Cohort Study
Ian Douglas Symposium Using Data from different Primary Care Software Management Systems
Liam Smeeth Presentation Trials and Clinical Care
Harriet Forbes Poster Quantification of Risk Factors For Postherpetic Neuralgia In Herpes Zoster Patients: A Cohort Study
Ruth Farmer Presentation Metformin and Cancer Risk in Type 2 Diabetes: An Application of Marginal Structural Models with Inverse Probability of Treatment Weights in the Clinical Practice Research Datalink
Rohini Mathur Poster Population trends in the ten-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014
Rohini Mathur Symposium Optimal uses of Ethnicity data in  UK EHR
Kevin Wing Presentation Detection and Quantification of Flucloxacillin-Induced Liver Injury: A Population-Based Cohort Study
Kevin Wing Symposium EHR databases and predictive genetic tests for drug-induced liver injury
Krishnan Bhaskaran Symposium Usage of Cancer data within the CPRD
Anu Jain Poster Social determinants of zoster disease burden in England: A study using electronic health records