Asthma and COPD – how often do patients have both conditions?
04 Jun 2018
Asthma and COPD share many characteristics and symptoms, and the differential diagnosis between the two diseases can be difficult in primary care. Francis Nissen and colleagues have recently done a study to quantify how commonly patients with chronic obstructive pulmonary disease (COPD) have a concomitant diagnosis of asthma, and how commonly patients with asthma have a concomitant diagnosis of...
Quality of life, depression and anxiety in breast cancer survivors
03 May 2018
We know that some women may experience both physical and psychological changes after a diagnosis of breast cancer. In order to learn more about this, researchers in the EHR group, in collaboration with researchers at the Clinical Practice Research Datalink, are inviting women both with a previous diagnosis of breast cancer and those never diagnosed with cancer to answer some questions about their...
Quality of life, depression and anxiety in breast cancer survivors compared to women who didn’t have cancer
03 May 2018
Rationale Every year, thousands of women are diagnosed with breast cancer in England. The treatments that are now available help many women to live for a long time after their cancer diagnosis. Aim The aim of this study is to understand if women who have had a diagnosis of breast cancer in the past have more anxiety, depression or a poorer quality of life compared to women who have not had...
Professional Certificate in Pharmacoepidemiology & Pharmacovigilance – now accepting applications for 2018/19
18 Apr 2018
This 30-week examined introductory course is relevant to anyone working in areas related to the risk-benefit of medicines and drug safety. Organised by members of the EHR research group and including lectures and workshops led by experts from academia, regulatory authorities and the pharmaceutical industry, the course can be followed face-to-face at LSHTM in London (3 blocks of teaching in...
UKRI Innovation Fund Fellowships
12 Feb 2018
Three new three year UKRI Innovation Fund Fellowships have been awarded to researchers at LSHTM, aligned with Health Data Research UK, all three have strong links to the Electronic Health Records research group. Rosalind Eggo will be using linked health and environmental data to assess joint effects of air pollution and circulating infections on health outcomes. Caroline Minassian has developed...
Health Data Research UK
12 Feb 2018
We are delighted to report that LSHTM was part of a successful pan-London bid to be a founding substantive partner in Health Data Research UK, a major new initiative to further data science in the UK. The London partners are LSHTM, UCL, QMUL, Kings and Imperial. This is an exciting opportunity for LSHTM to help build a partnership across London. Computerised health related data offers enormous...
MRC LID Studentships
16 Nov 2017
The 2018-19 MRC LID Studentships are now open for application, and as part of that the projects list is now live on the web.
Young Scientists: Public Trust in using Electronic Health Records for Research
06 Nov 2017
The Electronic Health Records (EHR) group at LSHTM recently hosted a group of visiting Young Scientists during their visit to LSHTM in September 2017. Sinéad Langan and Erin Lafferty led this programme of work with major contributions from public engagement champions in the EHR team. The experience was highly enjoyable with great engagement between team members and the Young Scientists. This...
British Science Festival in Brighton
27 Sep 2017
Charlotte Warren-Gash attended the British Science Festival in Brighton this month as part of her British Science Association Media Fellowship. She visited events ranging from the ethics of bio-art to genome donation, and bioengineering to the psychology of parenting. Read her festival reports...
Wellcome Trust Biomedical Vacation Scholarship awarded
02 Jun 2017
Promoting Research amongst Undergraduate Students Dr Sarah-Jo Sinnott, Dr Ian Douglas and co-applicant Heather Eames have been awarded a Wellcome Trust Biomedical Vacation Scholarship. This award provides funding for undergraduate students (Heather Eames) to gain practical experience of the research process during the summer break. The aim is to encourage students to consider a career in...
British Science Association Media Fellowship awarded
01 Jun 2017
Dr Charlotte Warren-Gash has been awarded a 2017 Media Fellowship from the British Science Association. This scheme offers scientists a unique opportunity to work at a media outlet, be mentored by professional journalists and engage the public with science through the media. Charlotte’s placement will be hosted by BBC Radio Science. She will also report on the British Science Festival in...
Nephrology Journal Club
26 Apr 2017
Wednesday 26th April’s Nephrology Journal Club is going to be based on a recent paper written by members of out group. Laurie Tomlinson has also written a blog relating to the paper. We hope as many people as possible can get involved here, and using the hashtag #NephJC.
Even small reductions in kidney function after starting common blood pressure drugs are associated with increased risk
03 Apr 2017
Angiotensin converting enzyme inhibitors (ACEI) (drugs with names ending in –pril, e.g. enalapril) and angiotensin receptor blockers (ARB) (drugs with names ending in –sartan, e.g. losartan) are drugs that are commonly used to treat high blood pressure and heart failure. Current guidelines recommend that they should be stopped in people who have a reduction in kidney function (measured using...
New NIHR-funded post to study drug-treatment effects using observational data
30 Mar 2017
Dr Kevin Wing has taken up a 3-year NIHR-funded position to study the effectiveness of drugs for Chronic Obstructive Pulmonary Disease (COPD) within observational data. Using randomised controlled trial individual patient data from clinicalstudydatarequest.com and observational data from the Clinical Practice Research Datalink (CPRD), optimal methods for assessing COPD treatment effectiveness in...
How useful are observational data for drug regulatory decision making?
09 Mar 2017
We have just been awarded a grant by the Association of the British Pharmaceutical Industry to determine how observational research using electronic health records is used in the regulatory decision making process in Europe. Every year, many studies about drug risks and benefits are published, and they often rely on the use of electronic health records. What we don’t know is how useful these...
StatinWISE trial testimonial
23 Feb 2017
“StatinWISE will answer a really important question: whether the muscular aches and pains that lots of people have are actually caused by statins. One of the exciting things about the project is the way it brings together individual patient care with research. As well as giving an answer for every individual patient – allowing them to make an informed choice about their future...
New 100 million cohort in Brazil
22 Feb 2017
Working in partnership with Brazilian researchers, we have helped secure Wellcome funding to develop a new biomedical resource: the 100 million Brazilian linked data and datacenter. This resource will be built around “Cadastro-Unico”, a database of electronic records of over 100 million applicants to social protection programmes in Brazil. Records consist of detailed individual information on...
StatinWISE now recruiting!
03 Feb 2017
StatinWISE is a trial designed to find out whether the muscle symptoms experienced during statin use are caused by statins. Statins are the most commonly prescribed treatment in the UK. Severe side effects such as rhabdomyolysis are rare, but there is uncertainty about whether statins cause less severe symptoms like muscle pain and cramps. StatinWISE aims to find out whether statins cause...
Brazilian 100 million cohort
30 Jan 2017
We are working closely with researchers in Brazil to help establish a new cohort of over 100 million Brazilian people based on linked data (led by Professor Mauricio Barreto). The cohort will be built around “CADASTRO-UNICO” a database of electronic records of applicants to social protection programmes in Brazil. Records consist of detailed individual information on housing conditions,...
Real World Effectiveness of Medications for COPD
23 Jan 2017
We have recently been awarded a three year grant by the UK National Institute for Health Research to study how well medication for COPD works in routine clinical care, and in particular in patients not normally studied in randomised trials. To do this, we’ll be using primary care data from the Clinical Practice Research Datalink linked with Hospital Episode Statistics data. A novel and exciting...