Krishnan Bhaskaran

I have a background in mathematics and statistics and have worked in various areas of medical statistics and epidemiology. My main current interest is in investigating long-term health outcomes among people with a history of cancer. I have a Sir Henry Dale fellowship from the Wellcome Trust and Royal Society to look specifically at cardiovascular consequences of cancer and its treatment, and am also interested in mental health and other outcomes among cancer survivors. I also have an ongoing interest in pharmacoepidemiology more generally and run a short course on the practical issues involved in doing pharmacoepi studies.

Contact details

Related Publications

Bariatric Surgery in the United Kingdom: A Cohort Study of Weight Loss and Clinical Outcomes in Routine Clinical Care.

Douglas, IJ. Bhaskaran, K. Batterham, RL. Smeeth, L. 
PLoS Med, 2015; 12(12):e1001925.

Quantification of risk factors for postherpetic neuralgia in a cohort of herpes zoster patients

Forbes, H. Bhaskaran, K. Thomas, S. Smeeth, L. Clayton, T. Mansfield, K. Minassian, C. Langan, S.
Neurology, 2016; pii: 10.1212/WNL.0000000000002808.

A systematic review and meta-analysis of risk factors for postherpetic neuralgia.

Forbes, HJ. Thomas, SL. Smeeth, L. Clayton, T. Farmer, R. Bhaskaran, K. Langan, SM. 
Pain, 2016, Jan;157(1):30-54.

Glitazone Treatment and Incidence of Parkinson’s Disease among People with Diabetes: A Retrospective Cohort Study.

Brauer, R. Bhaskaran, K. Chaturvedi, N. Dexter, DT. Smeeth, L. Douglas, I. 
PLoS Med, 2015; 12(7):e1001854.

Data Resource Profile: Clinical Practice Research Datalink (CPRD).

Herrett, E. Gallagher, AM. Bhaskaran, K. Forbes, H. Mathur, R. van Staa, T. Smeeth, L.
Int J Epidemiol, 2015;44(3):827-36.

The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom.

Hayes, J.F.; Bhaskaran, K.; Batterham, R.; Smeeth, L.; Douglas, I.;
The effect of sibutramine prescribing in routine clinical practice on cardiovascular outcomes: a cohort study in the United Kingdom.
Int J Obes (Lond), 2015;

Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink.

Matthews, A. ; Langan, S.M. ; Douglas, I.J. ; Smeeth, L. ; Bhaskaran, K. ;
Phosphodiesterase Type 5 Inhibitors and Risk of Malignant Melanoma: Matched Cohort Study Using Primary Care Data from the UK Clinical Practice Research Datalink.
PLoS Med, 2016; 13(6):e1002037


Codelists available
Statin use and the risk of herpes zoster: a nested case-control study using primary care data from the UK Clinical Research Practice Datalink.

Matthews, A. ; Turkson, M. ; Forbes, H. ; Langan, S.M. ; Smeeth, L. ; Bhaskaran, K. ;
Statin use and the risk of herpes zoster: a nested case-control study using primary care data from the UK Clinical Research Practice Datalink.
Br J Dermatol, 2016;

Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study.

Forbes, H.J. ; Bhaskaran, K. ; Thomas, S.L. ; Smeeth, L. ; Clayton, T. ; Mansfield, K. ; Minassian, C. ; Langan, S.M. ;
Quantification of risk factors for postherpetic neuralgia in herpes zoster patients: A cohort study.
Neurology, 2016;

Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.

Root, A.A. ; Wong, A.Y. ; Ghebremichael-Weldeselassie, Y. ; Smeeth, L. ; Bhaskaran, K. ; Evans, S.J. ; Brauer, R. ; Wong, I.C. ; Navaratnam, V. ; Douglas, I. ;
Evaluation of the risk of cardiovascular events with clarithromycin using both propensity score and self-controlled study designs.
Br J Clin Pharmacol, 2016;

Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data.

Matthews, A. ; Herrett, E. ; Gasparrini, A. ; Van Staa, T. ; Goldacre, B. ; Smeeth, L. ; Bhaskaran, K. ;
Impact of statin related media coverage on use of statins: interrupted time series analysis with UK primary care data.
BMJ, 2016; 353:i3283

Prenatal Vitamin D and Offspring Wheezing.

Bhaskaran, K. ; Smeeth, L. ; Evans, S. ;
Prenatal Vitamin D and Offspring Wheezing.
JAMA, 2016; 315(24):2730

Quantification of risk factors for herpes zoster: population based case-control study.

Forbes HJ, Bhaskaran K, Thomas SL, Smeeth L, Clayton T, Langan SM.


Codelists available
Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.

Wing, K. ; Bhaskaran, K. ; Smeeth, L. ; van Staa, T.P. ; Klungel, O.H. ; Reynolds, R.F. ; Douglas, I. ;
Optimising case detection within UK electronic health records: use of multiple linked databases for detecting liver injury.
BMJ Open, 2016; 6(9):e012102

Oral Fluoroquinolone Use and Retinal Detachment.

Douglas, I.J. ; Root, A. ; Krishnan, B. ;
Oral Fluoroquinolone Use and Retinal Detachment.
JAMA Ophthalmol, 2016;

Metformin and cancer in type 2 diabetes: a systematic review and comprehensive bias evaluation.

Farmer, R.E. ; Ford, D. ; Forbes, H.J. ; Chaturvedi, N. ; Kaplan, R. ; Smeeth, L. ; Bhaskaran, K. ;
Metformin and cancer in type 2 diabetes: a systematic review and comprehensive bias evaluation.
Int J Epidemiol, 2016;

Prescription of renin-angiotensin system blockers and risk of acute kidney injury: a population-based cohort study.

Mansfield, K.E. ; Nitsch, D. ; Smeeth, L. ; Bhaskaran, K. ; Tomlinson, L.A. ;
Prescription of renin-angiotensin system blockers and risk of acute kidney injury: a population-based cohort study.
BMJ Open, 2016; 6(12):e012690

Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study.

Schmidt, M. ; Mansfield, K.E. ; Bhaskaran, K. ; Nitsch, D. ; Sørensen, H.T. ; Smeeth, L. ; Tomlinson, L.A. ;
Adherence to guidelines for creatinine and potassium monitoring and discontinuation following renin-angiotensin system blockade: a UK general practice-based cohort study.
BMJ Open, 2017; 7(1):e012818

Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014.

Mathur, R. ; Bhaskaran, K. ; Edwards, E. ; Lee, H. ; Chaturvedi, N. ; Smeeth, L. ; Douglas, I. ;
Population trends in the 10-year incidence and prevalence of diabetic retinopathy in the UK: a cohort study in the Clinical Practice Research Datalink 2004-2014.
BMJ Open, 2017; 7(2):e014444

Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study.

Schmidt, M. ; Mansfield, K.E. ; Bhaskaran, K. ; Nitsch, D. ; Sørensen, H.T. ; Smeeth, L. ; Tomlinson, L.A. ;
Serum creatinine elevation after renin-angiotensin system blockade and long term cardiorenal risks: cohort study.
BMJ, 2017; 356:j791

Do pre-diagnosis primary care consultation patterns explain deprivation-specific differences in net survival among women with breast cancer? An examination of individually-linked data from the UK West Midlands cancer registry, national screening programme and Clinical Practice Research Datalink

Morris, M.; Woods, L.M.; Bhaskaran, K.; Rachet, B.
Do pre-diagnosis primary care consultation patterns explain deprivation-specific differences in net survival among women with breast cancer? An examination of individually-linked data from the UK West Midlands cancer registry, national screening programme and Clinical Practice Research Datalink
Bmc Cancer, 2017; 17:11

Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality.

Søgaard, K.K. ; Farkas, D.K. ; Ehrenstein, V. ; Bhaskaran, K. ; Bøtker, H.E. ; Sørensen, H.T. ;
Pericarditis as a Marker of Occult Cancer and a Prognostic Factor for Cancer Mortality.
Circulation, 2017;

Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.

Wing, K. ; Bhaskaran, K. ; Pealing, L. ; Root, A. ; Smeeth, L. ; van Staa, T.P. ; Klungel, O.H. ; Reynolds, R.F. ; Douglas, I. ;
Quantification of the risk of liver injury associated with flucloxacillin: a UK population-based cohort study.
J Antimicrob Chemother, 2017; 72(9):2636-2646


Codelists available
Impact of intrathecal morphine analgesia on the incidence of pulmonary complications after cardiac surgery: a single center propensity-matched cohort study.

Ellenberger, C. ; Sologashvili, T. ; Bhaskaran, K. ; Licker, M. ;
Impact of intrathecal morphine analgesia on the incidence of pulmonary complications after cardiac surgery: a single center propensity-matched cohort study.
BMC Anesthesiol, 2017; 17(1):109

Herpes zoster risk after 21 specific cancers: population-based case-control study.

Hansson, E. ; Forbes, H.J. ; Langan, S.M. ; Smeeth, L. ; Bhaskaran, K. ;
Herpes zoster risk after 21 specific cancers: population-based case-control study.
Br J Cancer, 2017; 116(12):1643-1651

Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol.

Carreira, H. ; Williams, R. ; Müller, M. ; Harewood, R. ; Bhaskaran, K. ;
Adverse mental health outcomes in breast cancer survivors compared to women who did not have cancer: systematic review protocol.
Syst Rev, 2017; 6(1):162

Breast cancer recurrence after reoperation for surgical bleeding.

Pedersen, R.N. ; Bhaskaran, K. ; Heide-Jørgensen, U. ; Nørgaard, M. ; Christiansen, P.M. ; Kroman, N. ; Sørensen, H.T. ; Cronin-Fenton, D.P. ;
Breast cancer recurrence after reoperation for surgical bleeding.
Br J Surg, 2017;

Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study.

Sinnott, S.J. ; Mansfield, K.E. ; Schmidt, M. ; Bhaskaran, K. ; Smeeth, L. ; Nitsch, D. ; Tomlinson, L.A. ;
Biochemical monitoring after initiation of aldosterone antagonist therapy in users of renin-angiotensin system blockers: a UK primary care cohort study.
BMJ Open, 2017; 7(11):e018153

Promises and pitfalls of electronic health record analysis.

Farmer, R. ; Mathur, R. ; Bhaskaran, K. ; Eastwood, S.V. ; Chaturvedi, N. ; Smeeth, L. ;
Promises and pitfalls of electronic health record analysis.
Diabetologia, 2017;

Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.

Yates, T.A. ; Tomlinson, L.A. ; Bhaskaran, K. ; Langan, S. ; Thomas, S. ; Smeeth, L. ; Douglas, I.J. ;
Lansoprazole use and tuberculosis incidence in the United Kingdom Clinical Practice Research Datalink: A population based cohort.
PLoS Med, 2017; 14(11):e1002457

Chronic obstructive pulmonary disease and the risk of 12 cardiovascular diseases: a population-based study using UK primary care data.

Morgan, A.D. ; Rothnie, K.J. ; Bhaskaran, K. ; Smeeth, L. ; Quint, J.K. ;
Chronic obstructive pulmonary disease and the risk of 12 cardiovascular diseases: a population-based study using UK primary care data.
Thorax, 2018;

Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink.

Koppe, U. ; Nitsch, D. ; Mansfield, K.E. ; Mathur, R. ; Bhaskaran, K. ; Batterham, R.L. ; Smeeth, L. ; Douglas, I.J. ;
Long-term effects of bariatric surgery on acute kidney injury: a propensity-matched cohort in the UK Clinical Practice Research Datalink.
BMJ Open, 2018; 8(5):e020371

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3 May

Quality of life, depression and anxiety in breast cancer survivors

03 May 2018

We know that some women may experience both physical and psychological changes after a diagnosis of breast cancer. In order to learn more about this, researchers in the EHR group, in collaboration with researchers at the Clinical Practice Research Datalink, are inviting women both with a previous diagnosis of breast cancer and those never diagnosed with cancer to answer some questions about their...

3 May

Quality of life, depression and anxiety in breast cancer survivors compared to women who didn’t have cancer

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26 Apr

Nephrology Journal Club

26 Apr 2017

Wednesday 26th April’s Nephrology Journal Club is going to be based on a recent paper written by members of out group. Laurie Tomlinson has also written a blog relating to the paper. We hope as many people as possible can get involved here, and using the hashtag #NephJC.

30 Jun

Statins controversy linked to rise in UK patients stopping the treatment

30 Jun 2016

New research highlights potential public health impact of high profile health stories in the media. For more information click here. Anthony Matthews, Emily Herrett, Antonio Gasparrini, Antonio, Tjeerd van Staa, Ben Goldacre, Liam Smeeth, Krishnan Bhaskaran, Impact of statin media coverage on the use of statins in the UK: an interrupted time series analysis using primary care data, BMJ. DOI:...

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Royal Society event at Buckingham Palace

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